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| Name | Type | Slot | Bonuses | Effects | Requirements |
| Dagannoth Ribs | | | | | |
| Damp Sticks | | | | | |
| Damp Tinderbox | | | | | |
| Dark Bow | Weapon | | Ranged Bonus: +95 | | Ranged: 60 |
| Dark Cavalier | | | | | |
| Darklight | | Primary | | | |
| Dead Sea Slug | | | | | |
| Death Rune | | | | | |
| Delphinium Seed | | | | | |
| Demonic Sigil | | | | | |
| Demonic Tome | | | | | |
| Denath's Sigil | | | | | |
| Dharok Greataxe | Weapon | | Crush Attack +95, Ranged Defense -1, Slash Attack +103, Stab Attack -4, Strength +105 | | Attack: 70, Strength: 70 |
| Dharok Helmet | Armor | Head | Crush Defense +44, Magic Attack -3, Magic Defense -1, Ranged Attack -1, Ranged Defense +51, Slash Defense +48, Stab Defense +45 | | Defense: 70 |
| Dharok Platebody | Armor | Body | Crush Defense +107, Magic Attack -30, Magic Defense -6, Ranged Attack -10, Ranged Defense +132, Slash Defense +120, Stab Defense +122 | | Defense: 70 |
| Dharok Platelegs | Armor | Legs | Crush Defense +83, Magic Attack -21, Magic Defense -4, Ranged Attack -7, Ranged Defense +92, Slash Defense +82, Stab Defense +85 | | Defense: 70 |
| Diamond | | | | | |
| Diamond Bauble | | | | | |
| Diary | | | | | |
| Dirty Robes | Armor | Body | | | |
| Distillator | | | | | |
| Distilled Tar | | | | | |
| Diving Helmet | | Head | | | |
| Doctors Gown | Armor | Body | | | |
| Doctors Hat | Armor | Head | | | |
| Doogle Leaf | | | | | |
| Dragon Arrows | | Ammo | | | |
| Dragon Axe | Weapon | Primary | | | |
| Dragon Battle Axe | Weapon | Primary | | | Attack: 60 |
| Dragon Bones | | | | | |
| Dragon Chainbody | Armor | Body | Crush Defense +98, Magic Attack -15, Magic Defense -3, Ranged Defense +82, Slash Defense +93, Stab Defense +81 | | Defense: 60 |
| Dragon Dagger | Weapon | Primary | Crush Attack -4, Slash Attack +25, Stab Attack +40, Strength +40 | | Attack: 60 |
| Dragon Halberd | Weapon | Primary | Crush Defense +5, Magic Attack -4, Slash Attack +95, Slash Defense +4, Stab Attack +70, Stab Defense -1, Strength +80 | Sweep | Attack: 60 |
| Dragon Longsword | Weapon | Primary | Crush Defense +2, Slash Attack +69, Slash Defense +3, Stab Attack +58 | | Attack: 60 |
| Dragon Mace | Weapon | Primary | | | |
| Dragon Medium Helmet | Armor | Head | Crush Defense +32, Magic Attack -3, Magic Defense -1, Ranged Attack -1, Ranged Defense +34, Slash Defense +35, Stab Defense +33 | | Defense: 60 |
| Dragon Platelegs | Armor | Legs | Crush Defense +63, Magic Attack -21, Magic Defense -4, Ranged Attack -7, Ranged Defense +65, Slash Defense +66, Stab Defense +68 | | Defense: 60 |
| Dragon Scale Dust | | | | | |
| Dragon Scimitar | Weapon | Primary | Crush Attack +6, Slash Attack +67, Slash Defense +1, Stab Attack +8 | | Attack: 60 |
| Dragon Spear | Weapon | Primary | Crush Attack +55, Slash Attack +55, Stab Attack +55, Strength +55 | | Attack: 60 |
| Dragon Square Shield | Armor | Secondary | Crush Defense +48, Magic Attack -6, Ranged Attack -2, Ranged Defense +50, Slash Defense +52, Stab Defense +50 | | Defense: 60 |
| Dragon Two-Handed Sword | Weapon | Primary | Crush Attack +80, Magic Attack -4, Ranged Defense -1, Slash Attack +92, Stab Attack -4, Strength +93 | Powerstab (AE) | Strength: 60 |
| Dragonfire Shield | Armor | Off Hand | Magic Attack -10, Ranged Attack -5, Stab Defense +70, Slash Defense +75, Crush Defense +72, Magic Defense +10, Ranged Defense +72, Strength +7 | | Defense: 75 |
| Dramen Staff | Weapon | Primary | | | |
| Draynor Skull | | | | | |
| Dried Orange Slices | | | Mining +1, Smithing +1 | | |
| Dry Sticks | | | | | |
| Dulphinium Seed | | | | | |
| Dung | | | | | |
| Dust Rune | | | | | |
| Dusty Key | | | | | |
| Dwarf Remains | | | | | |
| Dwarven Stout | Drink | | Mining +1, Smithing +1 | | |
| Dwell Berry | | | | | |
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