RuneScape Harvestables - S
| Name | Skill | Location |
| Salmon | Fishing | Ardougne, Lumbridge, Seer Village, Shilo Village |
| Sandstone | Mining | |
| Sardine | Fishing | Catherby, Draynor, Karamja |
| Sea Turtle | Fishing | Port Khazard |
| Shark | Fishing | Catherby |
| Shrimp | Fishing | Catherby, Draynor, Karamja |
| Silver | Mining | Al Kharid, Edgeville Dungeon, Karamja, Varrock |
| Slimey Eel | Fishing | Lumbridge, Mort Myre |
| Swordfish | Fishing | Brimhaven, Catherby, Karamja |
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